Missions

SpacePharma’s Experiments in Microgravity

OUR miniaturized ISS labs

SpaceX CRS-34

BSGN - SPANCER

SpacePharma launched its eleventh microgravity lab to the ISS, this mission will investigate potential therapies using 3D lung cancer tissue models in microgravity.

scheduled to Launch

MAY 2026

Figure 1 - Spancer Project Logo

OUR miniaturized ISS labs

BSGN - HORUS & Haifa university - Longevity

SpacePharma launched its tenth microgravity lab to the ISS , two additional experiments is set to investigate the effects of microgravity on human health. The Longevity experiment is set to examine telomere length in samples from individuals over 100 years old to explore how the microgravity environment may influence cellular aging. The Horus experiment is set to analyze gene expression in brain tumor samples from patients, investigating how microgravity conditions affect tumor-related gene activity.

Launched

APRIL 2026

/ Figure 1 - NG-24 mission patch

OUR miniaturized ISS labs

SpaceX CRS-33

BSGN Zeprion2 & SpacePharma mAb crystallization

SpacePharma launched its ninth microgravity lab to the ISS on board the SpaceX vehicle, with the experiment returning in March 2026, and the results are currently under analysis.

Launched

August 2025

SpacePharma Advanced (SPAd) lab abourd the ISS

Figure 1 - Zeprion2 mission patch

Figure 2 - SpacePharma's SPAd on board of the ISS

private space mission

SpaceX Fram2

Protein crystallization

SpacePharma, in collaboration with SpaceOmix, flew an experiment on the private SpaceX Fram2 mission to study protein crystallization. This mission of three and a half days had a polar orbit and did not dock to the ISS. The mission was prepared in mere weeks, demonstrating the transformative potential of private spaceflight for driving space-based R&D and manufacturing.

Launched

April 2025

Figure 1 SpaceOmix's payload containing SpacePharma's experimental hardware on board the Fram2 mission

OUR miniaturized ISS labs

SpaceX CRS-30

mAb crystallization technology demonstration

SpacePharma launched its sixth microgravity lab to the ISS on board the SpaceX vehicle, with the experiment returning to earth in April 2024.

Launched

March 2024

Figure 1

OUR miniaturized ISS labs

NG-19

Prion disease research mission

SpacePharma launched its fifth microgravity lab to the ISS on board of the Northrop Grumman Cygnus spacecraft, with the experiment returning to earth in September 2023.

Launched

August 2023

Figure 1 NG-19 mission patch

OUR miniaturized ISS labs

SpaceX CRS-27

The newest successful experiment onboard the ISS

SpacePharma launched its fourth microgravity lab to the ISS on board SpaceX vehicle, the experiment returned to earth on April 2023.

Launched

March 2023

Figure 1 SpacePharma Advanced lab (SPAd) being prepared for the CRS-27 mission

Figure 2 CRS-27 SpaceX Dragon loaded with SpacePharma's experiments ready for launch to space

Figure 3 SpaceX CRS-27 launching SpacePharma's SPAd to the ISS

Skin Tissue in Space

cultivation of human skin cells (keratinocytes and fibroblasts) in 2D or 3D culture systems to assess their ability to produce extracellular matrices, and also look at the cells’ properties, such as proliferation and their ability to migrate. The aim is to deepen the understanding of fundamental biological processes and potentially support the development of new therapies, devices and tools for wound healing, aging, and scarring.

Nanoemulsions

Production of phyto-nanoemulsion of a well-known plant under microgravity. This unique environment will potentially create a stronger therapeutical effect and a high stability for the final product, as emulsion properties are enhanced in microgravity, for example coalescence is much slower.

OUR miniaturized ISS labs

SPAd 2

5th generation lab onboard the ISS

SpacePharma launched its third microgravity lab to the ISS on board of SpaceX Axiom1 mission and returned to earth on April 25th 2022.

Launched

April 2022

Eytan stibbe ISS SpacePharma Advanced (SPAd) lab

Figure 1 Israeli astronaut Eytan Stibbe unloading SpacePharma's SPAd system for operations on the ISS

Figure 2 SPAd-lab and first private space mission Axiom-1 patch

Figure 3 SpaceX Dragon on the Axiom-1 mission arriving to the ISS carrying SpacePharma's SPAd

Meat for Space

Examining the ability of cow cells to mature into cells that build muscle tissue, the steak, under microgravity conditions

Interrogation of the Stress and DNA Damage Response During Space Flight

The purpose was to explore the effect of both magnetic field and microgravity. Apparently in parabolic flight no significant differences were observed.

Polymorphism of Organic Crystals

Crystallization of Histidine was performed in a flow system by adding antisolvent, in timing with airplane dives. Higher tendency towards the more stable polymorph A in flight, compared to Higher tendency towards the less stable polymorph B on ground was observed. It Indicates that initial seeding in microgravity determines polymorph of entire crystal population.

OUR miniaturized ISS labs

SPAd

SpacePharma advenced lab at the ISS

Launched

December 2021

The third microgravity lab to the ISS on board of SpaceX SPX-24 and returned to earth on January 24th 2022, in collaboration with Ramon Foundation.

SpacePharma team during NEXUS1 preflight

Figure 1 SpacePharma SPAd on the ISS during the CRS-24 mission

Figure 2 SpacePharma CEO Yossi Yamin with the SPAd prior to handover for the CRS-24 mission

SPmg2 lab ready to be installed to NEXUS1 and launch to the ISS

Figure 3 SpaceX Dragon approaching the ISS on the CRS-24 mission carrying SpacePharma's SPAd

M&M - Metformin and Muscles

Effect of microgravity on the regeneration process of human skeletal muscles cells.

Motor Neurons

Study the effect of microgravity on gene expression in the destruction process of motor neurons cells

Biomechanical Effects on the Interactions of Cancer Cells with Nano Carriers

Explore the biomechanical characteristics of cancer cells and the effect of antitumor drugs loaded in nanocarriers (Doxil liposomes) under microgravity conditions.

The Effect of Sub-gravity on Malignant Cells

Changes in RNA expression in Jurkat cancer cells (T-ALL cell line) exposed to microgravity

OUR SATELLITEs

DIDO 3

Free orbit satellite

Launched

SEP 2020

The Second free orbit autonomous and remoted controlled nanosatellite was launched including 4 scientific experiments for Israeli and Italian Universities and Hospitals.

Figure 2 SPmg2 lab ready to be installed in DIDO2 satellite

Figure 3 Droplet coalescence during 10 days experiment

Human serum albumin binding properties

investigate the heme binding to HSA in microgravity conditions as a prototypical model to establish whether gravity may affect the HSA capability to bind endogenous and exogenous molecule

Enzymatic Reaction

Investigate how microgravity environment of space affects the kinetics of the action of antimicrobial agents on bacterial pathogens

Antibiotic resistance

Bacterial conjugation, dissemination of antibiotic resistance genes and their expression control under microgravity conditions

DNA structure

Reconfiguration of DNA structures and their functions under no gravity conditions

OUR miniaturized ISS labs

SpaceX CRS-33

BSGN Zeprion2 & SpacePharma mAb crystallization

SpacePharma launched its sevent microgravity lab to the ISS on board the SpaceX vehicle, with the experiment returning in March 2026, and the results are currently under analysis.

Launched

August 2025

Figure 1 - Zeprion2 mission patch

Figure 2 - SpacePharma's SPAd on board of the ISS

OUR miniaturized ISS labs

SpaceX CRS-33

BSGN Zeprion2 & SpacePharma mAb crystallization

SpacePharma launched its sevent microgravity lab to the ISS on board the SpaceX vehicle, with the experiment returning in March 2026, and the results are currently under analysis.

Launched

August 2025

Figure 1 - Zeprion2 mission patch

Figure 2 - SpacePharma's SPAd on board of the ISS

OUR miniaturized ISS labs

SpaceX CRS-33

BSGN Zeprion2 & SpacePharma mAb crystallization

SpacePharma launched its sevent microgravity lab to the ISS on board the SpaceX vehicle, with the experiment returning in March 2026, and the results are currently under analysis.

Launched

August 2025

Figure 1 - Zeprion2 mission patch

Figure 2 - SpacePharma's SPAd on board of the ISS

OUR miniaturized ISS labs

Nexus 2

2nd generation lab onboard the ISS

This mission carried human muscle cells from 7 human donors in order to explore their growth and behavior.

Launched

NOV 2018

Figure 3 SpacePharma Advanced (SPAd) lab

Figure 2 SPAd-lab during NEXUS2 preflight

Figure 3 NEXUS2 launch to the ISS onboard of the NG10 resupply mission

Parabolic flights

SpacePharma has participated in three Parabolic flights to test the hardware and perform short experiments.

Organometalic Catalysis

The purpose was to explore the effect of both magnetic field and microgravity. Apparently in parabolic flight no significant differences were observed.

Polymorphism of Organic Crystals

OUR miniaturizedISS labs

Nexus 1

1st generation lab onboard the ISS

Launched

NOV 2017

Figure 4 Taking out product from NEXUS1 after successful return to Earth

Figure 2 SpacePharma team during NEXUS1 preflight

Figure 3 SpacePharma team during NEXUS1 preflight

Figure 4 SPmg2 lab ready to be installed to NEXUS1 and launch to the ISS

Crystallization of an active pharmaceutical ingredient for Asthma

Precipitation by anti-solvent and by cooling profile were tried. Crystals were ~100 times thicker and 10 times longer than earth needle-like crystals. Crystals had single lattice, providing accurate XRD data for determination of enantiomeric conformation.

Primary human macrophages adaptation to µG

Study of the activity of macrophages in space. Purpose was to understand the immunition system of astronauts.

OUR SATELLITEs

DIDO 2

Free orbit satellite

Launched

Feb 2017

Figure 5 DIDO2 satellite ready to go

Figure 2 SPmg2 lab ready to be installed in DIDO2 satellite

Figure 3 Droplet coalescence during 10 days experiment

c6h12o6

Enzymatic reaction

Glucose is oxidized by oxido-reductase in presence of Resazurin as an indicator. Reaction is monitored by spectrometry. Results showed that Kinetics was tenfolds slower, and different ratio of secondary oxidation were obtained.

h2o

Droplet coalescence

Oil droplets were suspended in water with surfactant. They were observed by optical microscope. It was found that Minimal drop coalescence occurred, compared to immediate phase separation on earth. Input for computerized kinetic simulation was provided by this experiment.

c9h11No2

Peptide self assembly

Phenyl-Alanine was precipitated by water and observed by optical microscope. Spherulite-like structures were obtained in microgravity, compared to sheaves structure on ground.

Past Missions

SpacePharma’s Experiments in Microgravity

SpaceX CRS-34

BSGN - SPANCER

BSGN - HORUS & Haifa university - Longevity

SpaceX CRS-33

BSGN Zeprion2 & SpacePharma mAb crystallization

SpaceX Fram2

Protein crystallization

SpaceX CRS-30

mAb crystallization technology demonstration

NG-19

Prion disease research mission

SpaceX CRS-27

The newest successful experiment onboard the ISS

SPAd 2

5th generation lab onboard the ISS

SPAd

SpacePharma advenced lab at the ISS

DIDO 3

Free orbit satellite

SpaceX CRS-33

BSGN Zeprion2 & SpacePharma mAb crystallization

SpaceX CRS-33

BSGN Zeprion2 & SpacePharma mAb crystallization

SpaceX CRS-33

BSGN Zeprion2 & SpacePharma mAb crystallization

Nexus 2

2nd generation lab onboard the ISS

Nexus 1

1st generation lab onboard the ISS

DIDO 2

Free orbit satellite